MGMT Antikörper (AA 1-100) (Biotin)
Kurzübersicht für MGMT Antikörper (AA 1-100) (Biotin) (ABIN7091485)
Target
Alle MGMT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-100
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Kreuzreaktivität
- Ratte
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Homologie
- Human,Mouse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from mouse MGMT
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Isotyp
- IgG
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Applikationshinweise
- WB 1:300-5000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
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Andere Bezeichnung
- MGMT
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Hintergrund
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Synonyms: 6 O methylguanine DNA methyltransferase, Agat, AGT, AI267024, EC 2.1.1.63, Methylated DNA protein cysteine methyltransferase, Methylguanine DNA methyltransferase, MGC107020, MGMT: O-6 methylguanine DNA methyltransferase, O 6 methylguanine DNA alkyltransferase, O 6 methylguanine DNA methyltransferase, O-6 methylguanine DNA alkyltransferase, O-6-methylguanine-DNA methyltransferase, O6 methylguanine DNA methyltransferase, MGMT_HUMAN.
Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
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Gen-ID
- 17314
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UniProt
- P26187
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Pathways
- DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus
Target
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