Rekombinanter MSH6 Antikörper

Produktnummer ABIN7091434

Der Kaninchen Monoklonal anti-MSH6 Antikörper wird verwendet zum Nachweis von MSH6 in Proben von Human. Er wurde validiert für WB, FACS, IHC (p), IF (p) und IHC (fro).

Kurzübersicht für Rekombinanter MSH6 Antikörper (ABIN7091434)

Target: MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MSH6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-MSH6 Antikörper

Verwendungszweck: MSH6 Recombinant Antibody

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MSH6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(WB(1:1000-5000)), FCM(FCM(1 μg/Test)), IHC-P(IHC-P(1:200-800)), IHC-F(IHC-F(1:200-800)), IF(IHC-P)(IF(IHC-P)(1:200-800))

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu MSH6

Target: MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

Andere Bezeichnung: MSH6

Hintergrund:

Synonyms: DNA mismatch repair protein MSH6, G/T mismatch binding protein, GTBP, GTMBP, HNPCC 5, HNPCC5, HSAP, MSH 6, mutS (E. coli) homolog 6, MutS alpha 160 kDa subunit, mutS homolog 6, p160, Sperm associated protein, MSH6_HUMAN, MutS Protein Homolog 6.

Background: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]

Gen-ID: 2956

UniProt: P52701

Pathways: DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response