LIN28B Antikörper
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- Target Alle LIN28B Antikörper anzeigen
- LIN28B (Lin-28 Homolog B (LIN28B))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser LIN28B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Homologie
- Human
- Immunogen
- Recombinant human LIN28B.
- Klon
- K7L3
- Top Product
- Discover our top product LIN28B Primärantikörper
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anti-Lin-28 Homolog B (LIN28B) (AA 95-128) antibody
LIN28B Reaktivität: Human WB, ELISA, IHC, FACS, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) (AA 1-30) antibodyLIN28B Reaktivität: Human WB, ELISA, IHC, FACS, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) (AA 166-250) antibodyLIN28B Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) antibodyLIN28B Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) (AA 218-250) antibodyLIN28B Reaktivität: Human WB, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) (AA 95-128) antibodyLIN28B Reaktivität: Human WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) antibodyLIN28B Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) (AA 161-250) antibodyLIN28B Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) (AA 200-250) antibodyLIN28B Reaktivität: Human, Affe IHC, IHC (p), IP Wirt: Kaninchen Polyclonal unconjugated
anti-Lin-28 Homolog B (LIN28B) (AA 218-250), (C-Term) antibodyLIN28B Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:300-5000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- LIN28B (Lin-28 Homolog B (LIN28B))
- Andere Bezeichnung
- LIN28B (LIN28B Produkte)
- Synonyme
- csdd2 antikoerper, LIN-28 antikoerper, CSDD2 antikoerper, 2810403D23Rik antikoerper, D030047M17Rik antikoerper, Lin-28.2 antikoerper, lin-28 homolog B antikoerper, lin-28 homolog B S homeolog antikoerper, lin-28 homolog B (C. elegans) antikoerper, LIN28B antikoerper, lin28b antikoerper, lin28b.S antikoerper, Lin28b antikoerper
- Hintergrund
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Synonyms: Lin-28B, LN28B_HUMAN, CSDD 2, CSDD2, FLJ16517, Lin 28 homolog B (C. elegans), Lin 28.2, Lin-28B, Protein lin-28 homolog B.
Background: Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation. Mediates MYC-mediated let-7 repression. Isoform 1, when overexpressed, stimulates growth of the breast adenocarcinoma cell line MCF-7. Isoform 2 has no effect on cell growth.
- Gen-ID
- 389421
- UniProt
- Q6ZN17
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