GZMB Antikörper (AA 21-130) (PE)
Kurzübersicht für GZMB Antikörper (AA 21-130) (PE) (ABIN7091176)
Target
Alle GZMB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 21-130
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Spezifität
- Specific towards Granzyme B and Granzyme H
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Kreuzreaktivität
- Human, Maus
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Homologie
- Rat,Cow,Pig
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human GZMB
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Isotyp
- IgG
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anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB Reaktivität: Human WB, IHC, StM Wirt: Maus Monoclonal GZMB-3014 unconjugated
anti-Granzyme B (GZMB) antibodyGZMB Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CLB-GB11 unconjugated
anti-Granzyme B (GZMB) (AA 21-130) antibodyGZMB Reaktivität: Human, Maus WB, ELISA, FACS, IHC (p), IF (p), IHC (fro), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 175-203), (C-Term) antibodyGZMB Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB19353 unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal 2G12G7 unconjugated
anti-Granzyme B (GZMB) (AA 1-247) antibodyGZMB Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB Reaktivität: Human IHC, StM Wirt: Maus Monoclonal GZMB-3056 unconjugated
anti-Granzyme B (GZMB) antibodyGZMB Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB Reaktivität: Human WB, IHC, IF, IHC (p) Wirt: Maus Monoclonal 4E4 unconjugated
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Applikationshinweise
- FCM 1:20-100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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- GZMB (Granzyme B (GZMB))
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Andere Bezeichnung
- Granzyme B
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Hintergrund
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Synonyms: HLP, CCPI, CGL1, CSPB, SECT, CGL-1, CSP-B, CTLA1, CTSGL1, Granzyme B, C11, CTLA-1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, T-cell serine protease 1-3E, GZMB, GRB, Granzyme B, Granzyme H
Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
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Gen-ID
- 3002
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UniProt
- P10144
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose
Target
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