CD3 Antikörper (Cy3)

Produktnummer ABIN7090886

Dieser Anti-CD3 Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von CD3 in FACS. Geeignet für Human.

Kurzübersicht für CD3 Antikörper (Cy3) (ABIN7090886)

Target: CD3

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD3 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Klon: HIT3b

Produktdetails anti-CD3 Antikörper (Cy3)

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human CD3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Details zu CD3

Target: CD3

Andere Bezeichnung: CD3

Hintergrund:

Synonyms: CD3e Molecule, CD3e Antigen, Epsilon Polypeptide (TiT3 Complex), T-Cell Surface Antigen T3/Leu-4 Epsilon Chain, CD3e Molecule, Epsilon (CD3-TCR Complex), T3E, T-Cell Antigen Receptor Complex, Epsilon Subunit Of T3, T-Cell Surface Glycoprotein CD3 Epsilon Chain, CD3e Antigen, CD3-Epsilon, IMD18, TCRE,

Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].

Gen-ID: 12501

UniProt: P22646

Pathways: T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway