PD-1 Antikörper (Biotin)
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- Target Alle PD-1 (PDCD1) Antikörper anzeigen
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PD-1 Antikörper ist konjugiert mit Biotin
- Applikation
- Bitte anfragen
- Produktmerkmale
- The clone 6D5, a mouse monoclonal antibody selectively binds with a 50-55 kD cell surface protein commonly known as Programmed cell death 1 (PD-1) or CD279, a member of the immunoglobulin superfamily. PD-1 expression is mostly observed in activated T cells and B cells, and also in dendritic cells. PD-1 signals via binding its two ligands, PD-L1 and PD-L2. Upon ligand binding, PD-1 signaling inhibits T-cell activation, leading to reduced proliferation, cytokine production, and T cell death. Blocking of PD-1 by its antibody restores T cells immunity against tumor and infectious agents. PD-1-blockade based immunotherapy is, therefore, highly clinically useful against various types of cancers and infectious diseases.
- Aufreinigung
- Purified
- Reinheit
- >95 %
- Güteklasse
- GMP Grade
- Immunogen
- PD1 transfected HEK293 cells
- Klon
- 6D5
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product PDCD1 Primärantikörper
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS pH 7.2, 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
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- Target
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- Andere Bezeichnung
- PD1 (PDCD1 Produkte)
- Synonyme
- CD279 antikoerper, PD-1 antikoerper, PD1 antikoerper, SLEB2 antikoerper, hPD-1 antikoerper, hPD-l antikoerper, Ly101 antikoerper, Pdc1 antikoerper, programmed cell death 1 antikoerper, PDCD1 antikoerper, Pdcd1 antikoerper
- Hintergrund
- The clone 6D5, a mouse monoclonal antibody selectively binds with a 50-55 kD cell surface protein commonly known as Programmed cell death 1 (PD-1) or CD279, a member of the immunoglobulin superfamily. PD-1 expression is mostly observed in activated T cells and B cells, and also in dendritic cells. PD-1 signals via binding its two ligands, PD-L1 and PD-L2. Upon ligand binding, PD-1 signaling inhibits T-cell activation, leading to reduced proliferation, cytokine production, and T cell death. Blocking of PD-1 by its antibody restores T cells immunity against tumor and infectious agents. PD-1-blockade based immunotherapy is, therefore, highly clinically useful against various types of cancers and infectious diseases.
- Gen-ID
- 5133
- UniProt
- Q15116
- Pathways
- Cancer Immune Checkpoints
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