ITGAL Antikörper (PE)
Kurzübersicht für ITGAL Antikörper (PE) (ABIN7076858)
Target
Alle ITGAL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- CD11a PE Antibody
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Produktmerkmale
- The clone TS1/22 recognizes a 170-180 kDa alpha chain of a type I transmembrane glycoprotein also known as CD11a or LFA-1a. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. CD11a is abundantly expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils but is not expressed by the non-hematopoietic tissues and platelets. Up-regulation of CD11a on activated lymphocytes is required to induce the immune response. Absence or reduced CD11a expression on tumor cells helps to escape from regular immune surveillance and may be a reason for in vivo tumor generation.
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Aufreinigung
- Purified
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Reinheit
- >95 %
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Immunogen
- Human HLA-DRCTL line cytolytic T-lymphocytes
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2-8°C, Conjugated antibodies should never be frozen.
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- ITGAL (Integrin alpha-L (ITGAL))
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Andere Bezeichnung
- CD11a
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Gen-ID
- 3683
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UniProt
- P20701
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Pathways
- Activated T Cell Proliferation, Integrin Complex
Target
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