PD-1 Antikörper (APC-iFluor™700)

Produktnummer ABIN7076774

Dieses Anti-PD-1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von PD-1 in FACS. Geeignet für Human.

Kurzübersicht für PD-1 Antikörper (APC-iFluor™700) (ABIN7076774)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PD-1 Antikörper ist konjugiert mit APC-iFluor™700

Applikation: Flow Cytometry (FACS)

Güteklasse: GMP Grade (Analyte)

Klon: 8G10

Produktdetails anti-PD-1 Antikörper (APC-iFluor™700)

Verwendungszweck: PD1 APC-iFluor700 Antibody

Produktmerkmale: The clone 8G10, a mouse monoclonal antibody selectively binds with a 50-55 kD cell surface protein commonly known as Programmed cell death 1 (PD-1) or CD279, a member of the immunoglobulin superfamily. PD-1 expression is mostly observed in activated T cells and B cells, and also in dendritic cells. PD-1 signals via binding its two ligands, PD-L1 and PD-L2. Upon ligand binding, PD-1 signaling inhibits T-cell activation, leading to reduced proliferation, cytokine production, and T cell death. Blocking of PD-1 by its antibody restores T cells immunity against tumor and infectious agents. PD-1-blockade based immunotherapy is, therefore, highly clinically useful against various types of cancers and infectious diseases.

Aufreinigung: Purified

Reinheit: >95 %

Immunogen: PD1 transfected HEK293 cells

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C, Conjugated antibodies should never be frozen.

Details zu PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Andere Bezeichnung: PD1

Gen-ID: 5133

UniProt: Q15116

Pathways: Cancer Immune Checkpoints