CD3 Antikörper (PE)

Produktnummer ABIN7076497

Der Maus Monoklonal Anti-CD3-Antikörper wurde für FACS validiert. Er ist geeignet, CD3 in Proben von Human zu detektieren.

Kurzübersicht für CD3 Antikörper (PE) (ABIN7076497)

Target: CD3

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD3 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Güteklasse: GMP Grade (Analyte)

Klon: SK7

Produktdetails anti-CD3 Antikörper (PE)

Verwendungszweck: CD3 PE Antibody

Produktmerkmale: The monoclonal SK7 clone recognizes antigen CD3ε epsilon, a 20KDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The CD3 complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor - CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. CD3ε is expressed on T lymphocytes, NK-T cells, and to a varying degree in developing thymocytes. CD3 plays central roles in TCR signaling, T lymphocyte activation, and antigen recognition.

Aufreinigung: Purified

Reinheit: >95 %

Immunogen: Human Thymocytes

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C, Conjugated antibodies should never be frozen.

Details zu CD3

Target: CD3

Andere Bezeichnung: CD3

Gen-ID: 916

NCBI Accession: NM_000733

UniProt: P07766

Pathways: T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway