PTPN12 Antikörper

Produktnummer ABIN7075292

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PTPN12 in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für PTPN12 Antikörper (ABIN7075292)

Target: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPN12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-PTPN12 Antikörper

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse PTPN12

Anwendungsinformationen

Applikationshinweise: WB (H,M,R) 1: 500-1: 800, IHC/IF (H,M,R) 1:1000-1:3000/1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu PTPN12

Target: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Andere Bezeichnung: PTPN12

Hintergrund: The PTPN12 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. The PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion. This suggests it has a regulatory role in controlling cell shape and mobility.

Molekulargewicht: 110 kDa

Gen-ID: 19248

NCBI Accession: NP_035333

UniProt: P35831