PARN Antikörper
Kurzübersicht für PARN Antikörper (ABIN7075117)
Target
Alle PARN Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse PARN
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Applikationshinweise
- WB (H,M) 1:500-1:1000, IHC/IF (H) 1:900-1:1800
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- PARN (Poly A Specific Ribonuclease (PARN))
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Andere Bezeichnung
- PARN
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Hintergrund
- The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Molekulargewicht
- 76 kDa
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Gen-ID
- 74108
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UniProt
- Q8VDG3
Target
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