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PARN Antikörper

PARN Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7262849
  • Target Alle PARN Antikörper anzeigen
    PARN (Poly A Specific Ribonuclease (PARN))
    Reaktivität
    • 38
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 28
    • 10
    Kaninchen
    Klonalität
    • 31
    • 7
    Polyklonal
    Konjugat
    • 26
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PARN Antikörper ist unkonjugiert
    Applikation
    • 27
    • 13
    • 11
    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human PARN (NP_002573.1).
    Isotyp
    IgG
    Top Product
    Discover our top product PARN Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IF 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PARN (Poly A Specific Ribonuclease (PARN))
    Andere Bezeichnung
    PARN (PARN Produkte)
    Synonyme
    parn-A antikoerper, xparn antikoerper, DAN antikoerper, RGD1565449 antikoerper, zgc:56067 antikoerper, 1200003I18Rik antikoerper, poly(A)-specific ribonuclease L homeolog antikoerper, poly(A)-specific ribonuclease antikoerper, poly(A)-specific ribonuclease (deadenylation nuclease) antikoerper, parn.L antikoerper, PARN antikoerper, Parn antikoerper, parn antikoerper
    Hintergrund
    The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht

    Observed_MW: 73 kDa

    Calculated_MW: 52 kDa/66 kDa/67 kDa/73 kDa

    Gen-ID
    5073
    UniProt
    O95453
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