Der Kaninchen Polyklonal anti-PARN Antikörper wird verwendet zum Nachweis von PARN in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA und IHC.
PARN
Reaktivität: Human, Maus
WB, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
IHC 1:50-1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.3 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
PARN
(Poly A Specific Ribonuclease (PARN))
Andere Bezeichnung
DAN
Hintergrund
This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development.