Der Kaninchen Polyklonal anti-KDM5A Antikörper (ABIN7074532) detektiert spezifisch KDM5A in WB.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.