KIF5B Antikörper
Kurzübersicht für KIF5B Antikörper (ABIN7074440)
Target
Alle KIF5B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Kreuzreaktivität
- Ratte
-
Aufreinigung
- Affinity purification
-
Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse KIF5B
-
-
-
-
Applikationshinweise
- WB (M,R) 1:2000-1:4000, IHC/IF (M,R) 1:500-1:1000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS, pH 7.4, 0.02 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
-
- KIF5B (Kinesin Family Member 5B (KIF5B))
-
Andere Bezeichnung
- KIF5B
-
Hintergrund
- Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. May be involved in the mechanisms of growth arrest induced by exposure to DNA-damaging drugs or by cellular senescence . Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner . Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation .
-
Molekulargewicht
- 130 kDa
-
Gen-ID
- 16573
-
NCBI Accession
- NP_032474
-
UniProt
- Q61768
-
Pathways
- Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization
Target
-