Der Kaninchen Polyklonal Anti-NEIL1-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, NEIL1 in Proben von Human, Ratte und Maus zu detektieren.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Target
NEIL1
(Endonuclease VIII-Like 1 (NEIL1))
Andere Bezeichnung
NEIL1
Hintergrund
NEIL1, also named as NEH1 and FPG1, belongs to the FPG family. It is involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. NEIL1 acts as DNA glycosylase that recognizes and removes damaged bases. It has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. NEIL1 has marginal activity towards 8-oxoguanine. It has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.