CMA1 Antikörper
Kurzübersicht für CMA1 Antikörper (ABIN7073506)
Target
Alle CMA1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Kreuzreaktivität
- Ratte
-
Aufreinigung
- Affinity purification
-
Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse Chymase
-
-
anti-Chymase 1, Mast Cell (CMA1) (Internal Region) antibody
Verified CMA1 Reaktivität: Human WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (C-Term) antibodyCMA1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 22-247) antibodyCMA1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 9-247) antibodyCMA1 Reaktivität: Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 1-247) antibodyCMA1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 22-247) antibodyCMA1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 22-197) antibodyCMA1 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 84-118) antibodyCMA1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB53046 unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 81-247) antibodyCMA1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) antibodyCMA1 Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal unconjugated
-
-
Applikationshinweise
- IHC/IF (M,R) 1:1000-1:2000/1:500-1:1000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS, pH 7.4, 0.02 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
-
- CMA1 (Chymase 1, Mast Cell (CMA1))
-
Andere Bezeichnung
- Mast Cell Chymase
-
Hintergrund
- This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases.
-
Gen-ID
- 17228
-
NCBI Accession
- NP_034910
-
UniProt
- P21844
-
Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
Target
-
