Rekombinanter CCR5 Antikörper (pSer337)

Produktnummer ABIN7072658

Der Kaninchen Chimeric Anti-CCR5-Antikörper wurde für WB, ELISA, FACS, IF und IP validiert. Er ist geeignet, CCR5 in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter CCR5 Antikörper (pSer337) (ABIN7072658)

Target: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CCR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: V14-2

Produktdetails anti-CCR5 Antikörper

Bindungsspezifität: pSer337

Verwendungszweck: Anti-CCR5 (phosphoserine 337) [V14/2], Rabbit IgG, kappa

Spezifität: V14/2 antibody has been demonstrated to exclusively recognise CCR5 (CD195) phosphorylated at Ser 337.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2b

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by immunizing mice with a synthetic phospho peptide corresponding to the C-Terminal region of human CCR5 conjugated to BSA.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: The V14/2 antibody is recommended for the specific detection and analysis of CCR5 phosphorylated on serine 337 (Pollok-Kopp et al., 2003). It was used in the detection of pS337 CCR5 in lysates of RBL-2H3 cells via Western blot (Pollok-Kopp et al., 2003). With other anti-CCR5 antibodies which react with nonphosporylated CCR5 (Ab01577) or CCR5 phosphorylated on different serine residues (Ab01578), it can be used to study dynamic regulation of CCR5 and of phosphorylation mechanisms.

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CCR5

Target: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Andere Bezeichnung: CCR5

Hintergrund: CD195, C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CHEMR13, HIV-1 fusion coreceptor, p337, pS337, Ser-337, Ser337

UniProt: P51681

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size