Rekombinanter CCR5 Antikörper (N-Term)

Produktnummer ABIN7072654

Dieser Maus Monoklonal Antikörper detektiert spezifisch CCR5 in WB, ELISA, FACS, IF und IP. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter CCR5 Antikörper (N-Term) (ABIN7072654)

Target: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: T21-8

Produktdetails anti-CCR5 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Anti-CCR5 [T21/8], Mouse IgG2a, kappa

Spezifität:

T21/8 antibody binds with high affinity to a CCR5 N-terminal epitope. CCR5 is a receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES.

Application Notes original Clone: T21/8 antibody is recommedned for the detection and analysis of CCR5 via various methods. For instance, one group used this antibody to detect intracellular localization of CCR5 in RBL-CCR5 cells via immunofluorescence staining (Pollok-Kopp et al., 2003). Another group investigated ligand-mediated down-modulation of CCR5 via flow cytometry, utilizing T21/8 antibody (Fox et al., 2015). With other anti-CCR5 antibodies which react with CCR5 phosphorylated on different serine residues (Ab01578, Ab01579), it can be used to study dynamic regulation of CCR5 and phosphorylation mechanisms.

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by immunizing mice with intact RBL-CCR5 cells.

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

OriginalSpeciesName: Mouse

OriginalFormat: IgG2a

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CCR5

Target: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Andere Bezeichnung: CCR5

Hintergrund: CD195, C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CHEMR13, HIV-1 fusion coreceptor

UniProt: P51681

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size