Rekombinanter MME Antikörper

Produktnummer ABIN7072622

Der Maus Monoklonal Anti-MME-Antikörper wurde für FACS, IHC und IF validiert. Er ist geeignet, MME in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter MME Antikörper (ABIN7072622)

Target: MME (Membrane Metallo-Endopeptidase (MME))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MME Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

Klon: FR4D11

Produktdetails anti-MME Antikörper

Verwendungszweck: Anti-CD10 [FR4D11], Mouse IgG1, kappa

Spezifität: FR4D11 antibody recognizes CD10. It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML).

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by immunizing mice with Raji cells.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: FR4D11 antibody can be used to identify and analyse neprilysin (CD10) via various techniques. For instance, it was utilized in the localization of neprilysin in human cerebral cortex via immunohistochemistry (Akiyama et al., 2001). This antibody was also used during a FACS analysis and phenotype characterization of Breast Cancer Stem Cells (BrCSCs) (Petrelli et al., 2015).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu MME

Target: MME (Membrane Metallo-Endopeptidase (MME))

Andere Bezeichnung: CD10

Substanzklasse: Chemical

Hintergrund: Neprilysin, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 24.11, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, EC 3.4.24, EC 3.4.24.11, FR4D11/F3

UniProt: P08473

Pathways: RTK Signalweg, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration