Rekombinanter CSF1R Antikörper

Produktnummer ABIN7072609

Dieser Ratte Monoklonal Antikörper detektiert spezifisch CSF1R in WB, IHC, FACS und BP. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für Rekombinanter CSF1R Antikörper (ABIN7072609)

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CSF1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Blocking Peptide (BP)

Klon: AFS98

Produktdetails anti-CSF1R Antikörper

Verwendungszweck: Anti-CD115/M-CSFR [AFS98], Rat IgG2a, kappa

Spezifität:

This antibody recognises mouse M-CSFR (CD115, CSF-1R) which is a membrane protein that influences tissue macrophage and osteoclast differentiation and proliferation.

Application Notes original Clone: AFS98 has been widely used in various flow cytometric analyses to label CD115 antigen. For instance, one group used it to detect monocytes in a mouse blood sample (Buschor et al., 2019). Similarly, Huo and colleagues (2017) utilised this antibody to identify monocytes in mouse blood in order to assess whether myelopoiesis was not a cause of the increase in the monocytes number. This antibody has been also successfully used to deplete macrophages (Ho et al., 2016). Finally, it was also utilised in the immunofluorescence staining of tissue sections prepared from 4 % paraformaldehyde-fixed and decalcified bones (Dong et al., 2016).

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised against CD115.

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

OriginalSpeciesName: Rat

OriginalFormat: IgG2a

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CSF1R

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Andere Bezeichnung: CD115/M-CSFR

Hintergrund: CSF-1R, Macrophage colony-stimulating factor 1 receptor, Csf1r, CD115, CSF-1 receptor, EC 2.7.10.1, CSF-1-R, M-CSF-R, Proto-oncogene c-Fms

UniProt: P09581

Pathways: RTK Signalweg, Inositol Metabolic Process, Cell-Cell Junction Organization