Rekombinanter CSF1R Antikörper

Produktnummer ABIN7072608

Dieses Anti-CSF1R-Antikörper ist ein Kaninchen Chimeric-Antikörper zur Detektion von CSF1R in WB, IHC, FACS und BP. Geeignet für Maus.

Kurzübersicht für Rekombinanter CSF1R Antikörper (ABIN7072608)

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CSF1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Blocking Peptide (BP)

Klon: AFS98

Produktdetails anti-CSF1R Antikörper

Verwendungszweck: Anti-CD115/M-CSFR [AFS98], Rabbit IgG, kappa

Spezifität: This antibody recognises mouse M-CSFR (CD115, CSF-1R) which is a membrane protein that influences tissue macrophage and osteoclast differentiation and proliferation.

Produktmerkmale:

Original Species of Ab: Rat

Original Format of Ab: IgG2a

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised against CD115.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: AFS98 has been widely used in various flow cytometric analyses to label CD115 antigen. For instance, one group used it to detect monocytes in a mouse blood sample (Buschor et al., 2019). Similarly, Huo and colleagues (2017) utilised this antibody to identify monocytes in mouse blood in order to assess whether myelopoiesis was not a cause of the increase in the monocytes number. This antibody has been also successfully used to deplete macrophages (Ho et al., 2016). Finally, it was also utilised in the immunofluorescence staining of tissue sections prepared from 4 % paraformaldehyde-fixed and decalcified bones (Dong et al., 2016).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CSF1R

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Andere Bezeichnung: CD115/M-CSFR

Hintergrund: CSF-1R, Macrophage colony-stimulating factor 1 receptor, Csf1r, CD115, CSF-1 receptor, EC 2.7.10.1, CSF-1-R, M-CSF-R, Proto-oncogene c-Fms

UniProt: P09581

Pathways: RTK Signalweg, Inositol Metabolic Process, Cell-Cell Junction Organization