Rekombinanter MARCO Antikörper
Kurzübersicht für Rekombinanter MARCO Antikörper (ABIN7072581)
Target
Alle MARCO Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-MARCO [PLK1], Rabbit IgG, kappa
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Spezifität
- This antibody recognises the extracellular domain V between residues 420 and 431 in MARCO both in human and bovine samples.
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG3
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Aufreinigung
- Protein A affinity purified
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Immunogen
- The antibody was raised by immunising BALB/c mice with human alveolar macrophages (AMs) and subsequent creation of hybridomas.
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Isotyp
- IgG kappa
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Applikationshinweise
- The specificity of this antibody was confirmed in an IF experiment where the antibody stained alveolar macrophages for MACRO (Arredouani et al., 2005). Tissue samples prepared in acetone and paraformaldehyde were also successfully immunohistochemically stained (Arredouani et al., 2005, Martens et al., 2006). The antibody was also capable of weak staining of alveolar macrophages in flow cytometry (Palecanda and Kobzik, 2001). In IP experiments, the antibody immunoprecipitates MARCO from lysates obtained from COS cells transfected with human MARCO (Arredouani et al., 2005).
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Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG3 format, for improved compatibility with existing reagents, assays and techniques.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
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Andere Bezeichnung
- MARCO
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Hintergrund
- SCARA2, macrophage receptor MARCO, macrophage receptor with collagenous structure, scavenger receptor class A member 2, PLK-1, PLK 1
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UniProt
- Q9UEW3
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Pathways
- Activation of Innate immune Response
Target
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