Rekombinanter IL-9 Antikörper

Produktnummer ABIN7072551

Dieses Anti-IL-9-Antikörper ist ein Kaninchen Chimeric-Antikörper zur Detektion von IL-9 in FACS und BP. Geeignet für Maus.

Kurzübersicht für Rekombinanter IL-9 Antikörper (ABIN7072551)

Target: IL-9 (IL9) (Interleukin 9 (IL9))

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser IL-9 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Blocking Peptide (BP)

Klon: D9302C12

Produktdetails anti-IL-9 Antikörper

Verwendungszweck: Anti-IL-9 [D9302C12], Rabbit IgG, kappa

Spezifität: This antibody is specific for murine IL-9.

Produktmerkmale:

Original Species of Ab: Hamster, Armenian

Original Format of Ab: IgG

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by immunising Armenian hamsters with Baculovirus-expressed, recombinant murine IL-9.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: In vitro, this antibody has inhibitory effects on IL-9 bioactivity, and inhibits the differentiation of Th17 cells and consequent production of IL-17 (Li et al, 2010). This antibody is also able to neutralise IL-9 in vivo (Li et al, 2010). Administration of this antibody suppresses acute experimental autoimmune encephalomyelitis (EAE), with an observed reduction in MOG-specific Th1 and Th17 cells in the periphery and the CNS (Li et al, 2010).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Hamster IgG2 format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu IL-9

Target: IL-9 (IL9) (Interleukin 9 (IL9))

Andere Bezeichnung: IL-9

Hintergrund: Interleukin-9, IL9, Cytokine P40, T-cell growth factor P40

UniProt: P15247

Pathways: JAK-STAT Signalweg