Rekombinanter IL-9 Antikörper
Kurzübersicht für Rekombinanter IL-9 Antikörper (ABIN7072550)
Target
Alle IL-9 (IL9) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-IL-9 [D9302C12], Hamster (Armenian) IgG, kappa
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Spezifität
- This antibody is specific for murine IL-9.
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Produktmerkmale
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Original Species of Ab: Hamster, Armenian
Original Format of Ab: IgG
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Aufreinigung
- Protein A affinity purified
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Immunogen
- This antibody was raised by immunising Armenian hamsters with Baculovirus-expressed, recombinant murine IL-9.
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Isotyp
- IgG kappa
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Applikationshinweise
- In vitro, this antibody has inhibitory effects on IL-9 bioactivity, and inhibits the differentiation of Th17 cells and consequent production of IL-17 (Li et al, 2010). This antibody is also able to neutralise IL-9 in vivo (Li et al, 2010). Administration of this antibody suppresses acute experimental autoimmune encephalomyelitis (EAE), with an observed reduction in MOG-specific Th1 and Th17 cells in the periphery and the CNS (Li et al, 2010).
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- IL-9 (IL9) (Interleukin 9 (IL9))
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Andere Bezeichnung
- IL-9
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Hintergrund
- Interleukin-9, IL9, Cytokine P40, T-cell growth factor P40
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UniProt
- P15247
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Pathways
- JAK-STAT Signalweg
Target
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