Rekombinanter RAGE Antikörper
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- Target Alle RAGE (AGER) Antikörper anzeigen
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Chimeric
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Konjugat
- Dieser RAGE Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Surface Plasmon Resonance (SPR)
- Verwendungszweck
- Anti-RAGE [2A11], Rabbit IgG, kappa
- Spezifität
- 2A11 is specific for the V-domain of human advanced glycosylation end product-specific receptor. It recognises both the glycosylated and non-glycosylated forms.
- Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
- Aufreinigung
- Protein A affinity purified
- Immunogen
- Human RAGE protein.
- Klon
- 2A11
- Isotyp
- IgG kappa
- Top Product
- Discover our top product AGER Primärantikörper
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anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 180-402) antibody
AGER Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 1-404) antibodyAGER Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 91-274) antibodyAGER Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 151-250) antibodyAGER Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IP, IF (cc), IF (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 23-404) antibodyAGER Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal 1C1 unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 91-120), (N-Term) antibodyAGER Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 76-104) antibodyAGER Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 206-234) antibodyAGER Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal RB21217 unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 24-52), (N-Term) antibodyAGER Reaktivität: Human, Maus WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB25948 unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 29-59), (N-Term) antibodyAGER Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB04825-04826 unconjugated
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- Applikationshinweise
- ELISA confirmed the specificity of 2A11 for the V-domain of RAGE, with a binding affinity (Kd) of 7.6 nM. ELISA was also used to confirm that the binding of 2A11 to RAGE is glycosylation independent. In SPR experiments the Kd of 2A11 binding to RAGE was determined as 0.38 nM. Flow cytometry and immunochemistry were used to visualise the binding of 2A11 to HEK-RAGE cells.
- Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
- Andere Bezeichnung
- RAGE (AGER Produkte)
- Hintergrund
- AGER, advanced glycosylation end product-specific receptor, receptor for advanced glycosylation end products
- Pathways
- Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteine
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