Rekombinanter IL-5 Antikörper

Produktnummer ABIN7072522

Dieses Kaninchen Chimeric-Antikörper erkennt spezifisch IL-5 in ELISA und Neut. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter IL-5 Antikörper (ABIN7072522)

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser IL-5 Antikörper ist unkonjugiert

Applikation: ELISA, Neutralization (Neut)

Klon: 2E3

Produktdetails anti-IL-5 Antikörper

Verwendungszweck: Anti-IL-5 [2E3], Rabbit IgG, kappa

Spezifität: This antibody is specific for human rIL-5, and does not cross-react with human rIL-1α, rIL-lβ, rIL-4, rIL-8, rM-CSF, or rTGF-α.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by immunising CAF1 mice with human recombinant IL-5.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody has been show to inhibit the binding of human rIL-5 to the alpha chain of the IL-5 receptor (Ames et al, 1995). This antibody inhibits the proliferation of murine B13 cells in response to human IL-5 (Ames et al, 1995).Neutralising antibodies against IL-5 represent a potential therapeutic strategy for the treatment of eosinophilia. The specificity of this antibody for human IL-5 has been confirmed in ELISA analysis (Ames et al, 1995).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu IL-5

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Andere Bezeichnung: IL-5

Hintergrund: Interleukin 5, IL5, IL 5, Eosinophil differentiation factor

UniProt: C9JQP9

Pathways: JAK-STAT Signalweg, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour