Rekombinanter MME Antikörper

Produktnummer ABIN7072451

Der Kaninchen Chimeric Anti-MME-Antikörper wurde für WB, IP und IF validiert. Er ist geeignet, MME in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter MME Antikörper (ABIN7072451)

Target: MME (Membrane Metallo-Endopeptidase (MME))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser MME Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Klon: NL-1

Produktdetails anti-MME Antikörper

Verwendungszweck: Anti-CD10 [NL-1], Rabbit IgG, kappa

Spezifität: This antibody reacts with human CD10. CD10 is a widely-expressed cell-surface metalloprotease, responsible for the cleavage of multiple peptide hormones at target tissues. CD10 is also a common marker for acute lymphocytic leukaemia.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Aufreinigung: Protein A affinity purified

Immunogen: BALB/c mice were immunised with acute lymphocytic leukaemia cells from a human leukaemia patient. Splenocytes were obtained from immunised mice and fused with MOPC-21 NS/1 myeloma cells to generate a hybridoma.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: NL-1 was shown to react with several leukaemic cell lines using immune adherence assays (Ueda et al, 1982). These authors also confirmed that NL-1 is specific for CD10 using IP.

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu MME

Target: MME (Membrane Metallo-Endopeptidase (MME))

Andere Bezeichnung: CD10

Substanzklasse: Chemical

Hintergrund: Neprilysin, Cluster of Differentiation 10, Membrane metallo-endopeptidase, MME, Neutral endopeptidase 24.11, Neutral endopeptidase, NEP, Common acute lymphocytic leukaemia antigen, CALLA, Skin fibroblast elastase, SFE, CMT2T, SCA43, Atriopeptidase, Enkephalinase

UniProt: P08473

Pathways: RTK Signalweg, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration