Rekombinanter PD-1 Antikörper
Kurzübersicht für Rekombinanter PD-1 Antikörper (ABIN7072412)
Target
Alle PD-1 (PDCD1) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-PD-1 [RMP1-14], Rabbit IgG, kappa
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Spezifität
- This antibody binds to murine PD-1.
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Produktmerkmale
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Original Species of Ab: Rat
Original Format of Ab: IgG2a
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Aufreinigung
- Protein A affinity purified
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Immunogen
- The original rat hybridoma was generated by immunizing Sprague Dawley rats with mouse PD-1-transfectked BHK cells. A P3U1 myeloma was used as the fusion partner.
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Isotyp
- IgG kappa
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Applikationshinweise
- Binding of the original rat IgG2a antibody to PD1 has been reported to prevent binding of both B7-H1-Ig (PD-L1-Ig) and B7-DC-Ig (PD-L2-Ig) fusion proteins to PD1.
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Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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Andere Bezeichnung
- PD-1
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Hintergrund
- CD279, PD1, PDCD1, RMPI-14, RMP1/14, Programmed Death Receptor 1, Programmed Death 1
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Pathways
- Cancer Immune Checkpoints
Target
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