Rekombinanter TGFA Antikörper
Kurzübersicht für Rekombinanter TGFA Antikörper (ABIN7072345)
Target
Alle TGFA Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-TGFalpha [tAb2], Mouse IgG2a, kappa
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Spezifität
- TAb2 binds the N-terminal sequence of transforming growth factor alpha, VVSHFND (with residues 4 to 7 being the minimal binding epitope).
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
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Aufreinigung
- Protein A affinity purified
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Immunogen
- Biologically active hemocyanin-coupled human TGFalpha.
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Isotyp
- IgG2a kappa
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Applikationshinweise
- Human transforming growth factora (TGFa) consists of 50 amino acid residues with three disulphide bridges. It belongs to the family of epidermal growth factor related peptides and binds to EGFreceptor. It is involved in cell proliferation in healthy cells and is found in various cancer cells. Transfection of Fibroblasts with the TGFa gene induces tumor formation.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- TGFA (Transforming Growth Factor, alpha (TGFA))
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Andere Bezeichnung
- TGFalpha
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Hintergrund
- TGFA, Transforming growth factor A
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UniProt
- P01135
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Pathways
- NF-kappaB Signalweg, RTK Signalweg, EGFR Signaling Pathway
Target
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