DPP4 Antikörper (PE)

Produktnummer ABIN7013983

Der Ratte Monoklonal Anti-DPP4-Antikörper wurde für FACS validiert. Er ist geeignet, DPP4 in Proben von Maus zu detektieren.

Kurzübersicht für DPP4 Antikörper (PE) (ABIN7013983)

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser DPP4 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: H194-112

Produktdetails anti-DPP4 Antikörper (PE)

Verwendungszweck: Anti-Ms CD26 PE

Spezifität: The rat monoclonal antibody H194-112 recognizes an extracellular epitope of CD26, a 110 kDa type II membrane glycoprotein, which is a peptidase expressed on mature thymocytes, T cells (especially activated), B cells, NK cells and macrophages.

Aufreinigung: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: BALB/c thymocytes

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-5 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Andere Bezeichnung: CD26

Hintergrund: Dipeptidyl peptidase 4,CD26, also known as dipeptidyl peptidase IV (DPP-IV), is a homodimeric cell surface serine peptidase that degradates IFN-gamma-induced cytokines, acts as a T cell costimulatory molecule, and participates in multiple immunopathological roles in leukocyte homing and inflammation. Alterations in its peptidase activity are characteristic of malignant transformation. The enzymatic activity increases dramatically with tumour grade and severity. CD26 is expressed in various blood cell types, but also e.g. in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.,DPP4, TP103, ADCP-2, ADABP

Gen-ID: 13482

UniProt: P28843

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity