KIFAP3 Antikörper

Produktnummer ABIN7261082

Dieses Anti-KIFAP3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KIFAP3 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für KIFAP3 Antikörper (ABIN7261082)

Target: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIFAP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KIFAP3 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human KIFAP3 (NP_055785.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KIFAP3

Target: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Andere Bezeichnung: KIFAP3

Hintergrund: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras, one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 110 kDa

Calculated_MW: 82 kDa/86 kDa/91 kDa

Gen-ID: 22920

UniProt: Q92845

Pathways: Hedgehog Signalweg, Sensory Perception of Sound