PSMA7 Antikörper
Kurzübersicht für PSMA7 Antikörper (ABIN7260948)
Target
Alle PSMA7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Produktmerkmale
- Polyclonal Antibody
-
Aufreinigung
- Affinity purification
-
Immunogen
- Recombinant fusion protein of human PSMA7 (NP_002783.1).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
-
Andere Bezeichnung
- PSMA7
-
Hintergrund
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9.
-
Molekulargewicht
-
Observed_MW: 30 kDa
Calculated_MW: 16 kDa/20 kDa/27 kDa
-
Gen-ID
- 5688
-
UniProt
- O14818
-
Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Target
-