UNC13B Antikörper
Kurzübersicht für UNC13B Antikörper (ABIN7258666)
Target
Alle UNC13B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein of human UNC13B (NP_006368.3).
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000 IF 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- UNC13B (Unc-13 Homolog B (UNC13B))
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Andere Bezeichnung
- UNC13B
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Hintergrund
- This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
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Molekulargewicht
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Observed_MW: 210 kDa
Calculated_MW: 180 kDa/182 kDa
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Gen-ID
- 10497
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UniProt
- O14795
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Pathways
- Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
Target
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