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Endothelin 3 Antikörper

This anti-Endothelin 3 antibody (ABIN7257539) is a Rabbit Polyclonal antibody detecting Endothelin 3 in IHC. Suitable for Mouse.
Produktnummer ABIN7257539

Kurzübersicht für Endothelin 3 Antikörper (ABIN7257539)

Target

Alle Endothelin 3 (EDN3) Antikörper anzeigen
Endothelin 3 (EDN3)

Reaktivität

  • 33
  • 6
  • 4
  • 2
  • 1
  • 1
Maus

Wirt

  • 33
  • 3
Kaninchen

Klonalität

  • 34
  • 2
Polyklonal

Konjugat

  • 24
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Endothelin 3 Antikörper ist unkonjugiert

Applikation

  • 25
  • 13
  • 7
  • 5
  • 3
  • 3
  • 2
  • 1
Immunohistochemistry (IHC)
  • Produktmerkmale

    Polyclonal Antibody

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein of human EDN3 (NP_996917.1).

    Isotyp

    IgG
  • Applikationshinweise

    IHC 1:50-1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    Endothelin 3 (EDN3)

    Andere Bezeichnung

    EDN3

    Hintergrund

    The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Gen-ID

    1908

    UniProt

    P14138

    Pathways

    Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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