Endothelin 3 Antikörper (AA 168-197)

Produktnummer ABIN3030805

Produktdetails anti-Endothelin 3 Antikörper

Target: Endothelin 3 (EDN3)

Bindungsspezifität: AA 168-197

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Endothelin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 168-197 from the human protein was used as the immunogen for this EDN3 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the EDN3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the EDN3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Endothelin 3

Target: Endothelin 3 (EDN3)

Andere Bezeichnung: EDN3 (EDN3 Produkte)

Synonyme: et-3 antikoerper, EDN3 antikoerper, ET-3 antikoerper, ET3 antikoerper, HSCR4 antikoerper, PPET3 antikoerper, WS4B antikoerper, 114CH19 antikoerper, ls antikoerper, tmgc48 antikoerper, Et3 antikoerper, RGD1564825 antikoerper, preproET-3 antikoerper, endothelin-3 L homeolog antikoerper, endothelin 3 antikoerper, edn3.L antikoerper, EDN3 antikoerper, Edn3 antikoerper

Hintergrund: The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.

UniProt: P14138

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones