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CRADD Antikörper

CRADD Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7255548
$686.00
Zzgl. Versandkosten $45.00
Lieferung in 8 bis 11 Werktagen
  • Target Alle CRADD Antikörper anzeigen
    CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
    Reaktivität
    • 48
    • 4
    • 2
    Human, Maus
    Wirt
    • 42
    • 6
    • 1
    • 1
    Kaninchen
    Klonalität
    • 42
    • 8
    Polyklonal
    Konjugat
    • 29
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CRADD Antikörper ist unkonjugiert
    Applikation
    • 39
    • 24
    • 9
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human CRADD (NP_003796.1).
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
    Andere Bezeichnung
    CRADD (CRADD Produkte)
    Synonyme
    cradd antikoerper, MGC89035 antikoerper, zgc:101717 antikoerper, CRADD antikoerper, DKFZp468A2219 antikoerper, LOC100226369 antikoerper, raidd antikoerper, MGC78788 antikoerper, MRT34 antikoerper, RAIDD antikoerper, CASP2 and RIPK1 domain containing adaptor with death domain antikoerper, CASP2 and RIPK1 domain containing adaptor with death, gene 1 antikoerper, CASP2 and RIPK1 domain containing adaptor with death, gene 2 S homeolog antikoerper, CRADD antikoerper, cradd.1 antikoerper, cradd antikoerper, cradd.2.S antikoerper, Cradd antikoerper
    Hintergrund
    This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.
    Molekulargewicht

    Observed_MW: 22 kDa

    Calculated_MW: 11 kDa/22 kDa

    Gen-ID
    8738
    UniProt
    P78560
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
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