Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

CHEK2 Antikörper (pThr68)

Der Kaninchen Polyklonal anti-CHEK2 Antikörper wird verwendet zum Nachweis von CHEK2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IF und IHC (p).

Immunohistochemistry of paraffin-embedded Human uterus tissue using Phospho-CHEK2 (Thr68) Polyclonal Antibody at dilution of 1:200 (CHEK2 Antikörper (pThr68))

IHC (p)

Immunofluorescence analysis of Rat lung tissue using Phospho-CHEK2 (Thr68) Polyclonal Antibody at dilution of 1:200 (CHEK2 Antikörper (pThr68))

3 Abbildungen

Produktnummer ABIN7250719

449,00 €

Zzgl. Versandkosten 20,00 € und MwSt

Lieferung nach: Deutschland

Lieferung in 9 bis 13 Werktagen

Kurzübersicht für CHEK2 Antikörper (pThr68) (ABIN7250719)

Target

Alle CHEK2 Antikörper anzeigen

CHEK2 (Checkpoint Kinase 2 (CHEK2))

Reaktivität

Human, Maus, Ratte

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser CHEK2 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product CHEK2 Primärantikörper

Bindungsspezifität
34

26

20

17

16

16

15

15

9

8

8

8

6

4

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pThr68

Produktmerkmale

Phosphorylated antibody

Aufreinigung

Affinity purification

Immunogen

Synthesized peptide derived from human Chk2 around the phosphorylation site of Thr68

Isotyp

IgG
anti-Checkpoint Kinase 2 (CHEK2) (pThr387) antibody
CHEK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 111-141), (N-Term) antibody
CHEK2 Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB19067 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibody
CHEK2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 4B7 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibody
CHEK2 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pThr383) antibody
CHEK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pSer516) antibody
CHEK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pThr68) antibody
CHEK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reaktivität: Human, Affe, Hund WB, IHC, IF, IHC (p), FACS Wirt: Maus Monoclonal 10G7 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reaktivität: Human, Hund WB, IHC, IF, IHC (p), IP, FACS Wirt: Maus Monoclonal 5C4 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reaktivität: Human, Hund WB, IHC, IHC (p), IP, FACS Wirt: Maus Monoclonal 2H5 unconjugated

Applikationshinweise

WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:10000-1:20000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze / thaw cycles.
Target

CHEK2 (Checkpoint Kinase 2 (CHEK2))

Andere Bezeichnung

CHEK2

Hintergrund

Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20'.

Molekulargewicht

Observed_MW: 61 kDa
Calculated_MW: 61 kDa

UniProt

O96017

Pathways

p53 Signalweg, Apoptose, Zellzyklus