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CHEK2 Antikörper (pThr68)

Name: CHEK2 Antikörper (pThr68)
Brand: antibodies-online
SKU: ABIN7250719
Price: 538.8 EUR
Availability: InStock

Der Kaninchen Polyklonal Anti-CHEK2-Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, CHEK2 in Proben von Human, Maus und Ratte zu detektieren.

Western Blot analysis of Hela cells using Phospho-CHEK2 (Thr68) Polyclonal Antibody at dilution of 1:500 (CHEK2 Antikörper (pThr68))

Immunohistochemistry of paraffin-embedded Human uterus tissue using Phospho-CHEK2 (Thr68) Polyclonal Antibody at dilution of 1:200 (CHEK2 Antikörper (pThr68))

IHC (p)

Immunofluorescence analysis of Rat lung tissue using Phospho-CHEK2 (Thr68) Polyclonal Antibody at dilution of 1:200 (CHEK2 Antikörper (pThr68))

3 Abbildungen

Produktnummer ABIN7250719

Kurzübersicht für CHEK2 Antikörper (pThr68) (ABIN7250719)

Target

Alle CHEK2 Antikörper anzeigen

CHEK2 (Checkpoint Kinase 2 (CHEK2))

Reaktivität

Human, Maus, Ratte

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser CHEK2 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product CHEK2 Primärantikörper

Bindungsspezifität
25

24

19

17

16

16

15

15

9

8

8

8

5

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pThr68

Produktmerkmale

Phosphorylated antibody

Aufreinigung

Affinity purification

Immunogen

Synthesized peptide derived from human Chk2 around the phosphorylation site of Thr68

Isotyp

IgG
anti-Checkpoint Kinase 2 (CHEK2) (pThr387) antibody
CHEK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 111-141), (N-Term) antibody
CHEK2 Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB19067 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibody
CHEK2 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibody
CHEK2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 4B7 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pSer516) antibody
CHEK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pThr68) antibody
CHEK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pThr383) antibody
CHEK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reaktivität: Human, Hund WB, IHC, IHC (p), IP, FACS Wirt: Maus Monoclonal 2H5 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reaktivität: Human, Hund WB, IHC, IF, IHC (p), IP, FACS Wirt: Maus Monoclonal 5C4 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reaktivität: Human, Affe, Hund WB, IHC, IF, IHC (p), FACS Wirt: Maus Monoclonal 10G7 unconjugated

Applikationshinweise

WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:10000-1:20000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze / thaw cycles.
Target

CHEK2 (Checkpoint Kinase 2 (CHEK2))

Andere Bezeichnung

CHEK2

Hintergrund

Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20'.

Molekulargewicht

Observed_MW: 61 kDa
Calculated_MW: 61 kDa

UniProt

O96017

Pathways

p53 Signalweg, Apoptose, Zellzyklus