beta Catenin Antikörper
Kurzübersicht für beta Catenin Antikörper (ABIN7249752)
Target
Alle beta Catenin (CATNB) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Produktmerkmale
- Monoclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse beta-catenin
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:1000, IHC 1:100-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 420 μg/mL
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Buffer
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Andere Bezeichnung
- Catenin beta
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Hintergrund
- CTNNB1,also known as β-Catenin,is an evolutionarily conserved,multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs,CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .
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Molekulargewicht
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Observed_MW: 92 kDa
Calculated_MW: 92 kDa
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UniProt
- P35222, Q02248, Q9WU82
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Pathways
- Peptide Hormone Metabolism
Target
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