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TERT Antikörper

TERT Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7248992
  • Target Alle TERT Antikörper anzeigen
    TERT (Telomerase Reverse Transcriptase (TERT))
    Reaktivität
    • 102
    • 37
    • 20
    • 5
    • 1
    • 1
    Human
    Wirt
    • 105
    • 5
    • 1
    Kaninchen
    Klonalität
    • 97
    • 14
    Polyklonal
    Konjugat
    • 50
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser TERT Antikörper ist unkonjugiert
    Applikation
    • 65
    • 48
    • 38
    • 27
    • 17
    • 14
    • 13
    • 12
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Synthetic peptide of human TERT
    Isotyp
    IgG
    Top Product
    Discover our top product TERT Primärantikörper
  • Applikationshinweise
    WB 1:200-1:1000, IHC 1:25-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.1 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TERT (Telomerase Reverse Transcriptase (TERT))
    Andere Bezeichnung
    TERT (TERT Produkte)
    Hintergrund
    Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified, the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.
    Molekulargewicht
    127 kDa
    NCBI Accession
    NP_937983
    UniProt
    O14746
    Pathways
    Telomere Maintenance
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