TERT Antikörper (AA 627-656)

Produktnummer ABIN3029108

Produktdetails anti-TERT Antikörper

Target: TERT (Telomerase Reverse Transcriptase (TERT))

Bindungsspezifität: AA 627-656

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TERT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Aufreinigung: Purified

Immunogen: A portion of amino acids 627-656 from the human protein was used as the immunogen for this TERT antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the TERT antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the TERT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu TERT

Target: TERT (Telomerase Reverse Transcriptase (TERT))

Andere Bezeichnung: TERT (TERT Produkte)

Synonyme: CMM9 antikoerper, DKCA2 antikoerper, DKCB4 antikoerper, EST2 antikoerper, PFBMFT1 antikoerper, TCS1 antikoerper, TP2 antikoerper, TRT antikoerper, hEST2 antikoerper, hTRT antikoerper, chTERT antikoerper, Tert antikoerper, ATTERT antikoerper, F5E19.190 antikoerper, F5E19_190 antikoerper, telomerase reverse transcriptase antikoerper, tert antikoerper, TR antikoerper, est2 antikoerper, tcs1 antikoerper, telomerase antikoerper, tert-A antikoerper, tp2 antikoerper, trt antikoerper, xTERT antikoerper, telomerase reverse transcriptase antikoerper, Telomerase Reverse Transcriptase antikoerper, Tertp antikoerper, Telomerase catalytic subunit antikoerper, telomerase reverse transcriptase L homeolog antikoerper, TERT antikoerper, trt-1 antikoerper, Tert antikoerper, tert antikoerper, CMU_003490 antikoerper, VDBG_04487 antikoerper, GL50803_16225 antikoerper, tert.L antikoerper

Hintergrund: Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.

UniProt: O14746

Pathways: Telomere Maintenance