IFT57 Antikörper
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- Target Alle IFT57 Antikörper anzeigen
- IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IFT57 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), ELISA
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Antigen affinity purification
- Immunogen
- Fusion protein of human IFT57
- Isotyp
- IgG
- Top Product
- Discover our top product IFT57 Primärantikörper
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- Applikationshinweise
- IHC 1:50-1:300, ELISA 1:5000-1:10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.5 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
- Andere Bezeichnung
- IFT57 (IFT57 Produkte)
- Hintergrund
- Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.
- UniProt
- Q9NWB7
- Pathways
- Hedgehog Signalweg, Positive Regulation of Endopeptidase Activity
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