IL36A/IL1F6 Antikörper
Kurzübersicht für IL36A/IL1F6 Antikörper (ABIN7245296)
Target
Alle IL36A/IL1F6 (IL1F6) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Antigen affinity purification
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Immunogen
- Synthetic peptide of human IL36A
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.78 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))
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Andere Bezeichnung
- IL36A
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Hintergrund
- IL36A (Interleukin 36, Alpha) is a Protein Coding gene. Diseases associated with IL36A include Psoriasis. Among its related pathways are Innate Immune System and Toll-Like receptor Signaling Pathways. GO annotations related to this gene include cytokine activity and interleukin-1 receptor binding. An important paralog of this gene is IL36G.The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.
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Molekulargewicht
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Observed_MW: Refer to figures
Calculated_MW: 18 kDa
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UniProt
- Q9UHA7
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Pathways
- Cancer Immune Checkpoints
Target
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