IL36A/IL1F6 Antikörper (AA 21-70)

Produktnummer ABIN7229106

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IL36A/IL1F6 in ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für IL36A/IL1F6 Antikörper (AA 21-70) (ABIN7229106)

Target: IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL36A/IL1F6 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-IL36A/IL1F6 Antikörper

Bindungsspezifität: AA 21-70

Verwendungszweck: Rabbit Anti-IL-1F6 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of IL-1F6

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human IL-1F6 protein at AA range: 21-70

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu IL36A/IL1F6

Target: IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))

Andere Bezeichnung: IL-1F6

Hintergrund: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6The protein encoded by IL36A is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of IL36A has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. IL36A (Interleukin 36, Alpha) is a Protein Coding gene. Diseases associated with IL36A include Psoriasis. Among its related pathways are Toll-Like receptor Signaling Pathways and Cytokine Signaling in Immune system.

Gen-ID: 27179

UniProt: Q9UHA7

Pathways: Cancer Immune Checkpoints