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EGFR Antikörper (AA 888-1210)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch EGFR in WB und IHC. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7426025

Kurzübersicht für EGFR Antikörper (AA 888-1210) (ABIN7426025)

Target

Alle EGFR Antikörper anzeigen
EGFR (Epidermal Growth Factor Receptor (EGFR))

Reaktivität

  • 853
  • 301
  • 290
  • 25
  • 25
  • 24
  • 20
  • 14
  • 8
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 614
  • 240
  • 14
  • 13
  • 5
  • 4
  • 1
  • 1
  • 1
Maus

Klonalität

  • 546
  • 342
  • 2
Monoklonal

Konjugat

  • 467
  • 66
  • 28
  • 21
  • 18
  • 18
  • 18
  • 17
  • 16
  • 16
  • 16
  • 13
  • 13
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 9
  • 9
  • 9
  • 9
  • 9
  • 8
  • 8
  • 2
  • 1
  • 1
  • 1
Dieser EGFR Antikörper ist unkonjugiert

Applikation

  • 613
  • 265
  • 210
  • 169
  • 148
  • 129
  • 102
  • 93
  • 83
  • 82
  • 37
  • 34
  • 33
  • 27
  • 19
  • 11
  • 8
  • 6
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

Klon

C4
  • Bindungsspezifität

    • 42
    • 39
    • 31
    • 31
    • 30
    • 29
    • 27
    • 27
    • 26
    • 22
    • 22
    • 18
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 15
    • 13
    • 12
    • 12
    • 11
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    AA 888-1210

    Verwendungszweck

    Monoclonal Antibody to Epidermal Growth Factor Receptor (EGFR)

    Spezifität

    The antibody is a mouse monoclonal antibody raised against EGFR. It has been selected for its ability to recognize EGFR in immunohistochemical staining and western blotting.

    Aufreinigung

    Protein A + Protein G affinity chromatography

    Immunogen

    Recombinant Epidermal Growth Factor Receptor (EGFR) corresdonding to His888~Ala1210 with N-terminal His Tag

    Isotyp

    IgG2b kappa
  • Applikationshinweise

    Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

    Kommentare

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

    Haltbarkeit

    24 months
  • Target

    EGFR (Epidermal Growth Factor Receptor (EGFR))

    Andere Bezeichnung

    EGFR

    Hintergrund

    ErbB-1, ErbB1, ER1, ERB-B1, MENA, HER1, Erythroblastic Leukemia Viral(v-Erb-B)oncogene Homolog,Avian, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1

    UniProt

    P00533

    Pathways

    NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
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