GLIS2 Antikörper (AA 260-310)

Produktnummer ABIN6992104

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GLIS2 in WB, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für GLIS2 Antikörper (AA 260-310) (ABIN6992104)

Target: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLIS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GLIS2 Antikörper

Bindungsspezifität: AA 260-310

Spezifität: GLIS2 antibody is human, mouse and rat reactive.

Aufreinigung: GLIS2 antibody is affinity chromatography purified via peptide column.

Immunogen: GLIS2 antibody was raised against an 18 amino acid peptide near the center of human GLIS2. The immunogen is located within amino acids 260 - 310 of GLIS2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: GLIS2 antibody can be used for detection of GLIS2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: GLIS2 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: GLIS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu GLIS2

Target: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Andere Bezeichnung: GLIS2

Hintergrund: GLIS2, also known as neuronal Krueppel-like, is a 524 amino acid protein that belongs to the GLI C2H2-type zinc-finger protein family (1). GLIS2 can act either as a transcription repressor or as a transcription activator and may be involved in neuron differentiation (1,2). GLIS2 is expressed at high levels in kidney and at low levels in heart, lung and placenta. Mutations of GLIS2 have been suggested to be associated with development of progressive chronic kidney disease with characteristics resembling nephronophthisis (3,4).

Molekulargewicht: Predicted: 58 kDa

Observed: 60 kDa

Gen-ID: 84662

NCBI Accession: NP_115964

UniProt: Q9BZE0