PIK3C3 Antikörper (N-Term)

Produktnummer ABIN6992032

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PIK3C3 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für PIK3C3 Antikörper (N-Term) (ABIN6992032)

Target: PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIK3C3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PIK3C3 Antikörper

Bindungsspezifität: AA 130-180, N-Term

Spezifität: PIK3C3 antibody is human, mouse and rat reactive.

Aufreinigung: PIK3C3 antibody is affinity chromatography purified via peptide column.

Immunogen: PIK3C3 antibody was raised against an 18 amino acid peptide near the amino terminus of human PIK3C3. The immunogen is located within amino acids 130 - 180 of PIK3C3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PIK3C3 antibody can be used for detection of PIK3C3 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PIK3C3 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PIK3C3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu PIK3C3

Target: PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Andere Bezeichnung: PIK3C3

Hintergrund: PI 3-kinase p100 (phosphoinositide-3-kinase p100 subunit), also known as hVps34 or PIK3C3 (phosphoinositide-3-kinase class III), is a member of the PI3/PI4-kinase family (1). It is a catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate and ubiquitously expressed with a highest expression in skeletal muscle (1,2). PIK3C3 is involved in the endosome to lysosome transport and plays important roles in intracellular membrane trafficking and autophagy (3-5).

Molekulargewicht: Predicted: 91, 98 kDa

Observed: 98 kDa

Gen-ID: 5289

NCBI Accession: NP_002638

UniProt: Q8NEB9

Pathways: AMPK Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Toll-Like Receptors Cascades, Autophagie