FIL1h Antikörper (C-Term)

Produktnummer ABIN6991916

Der Kaninchen Polyklonal Anti-FIL1h-Antikörper wurde für WB, ELISA, IHC (p) und IF validiert. Er ist geeignet, FIL1h in Proben von Human zu detektieren.

Kurzübersicht für FIL1h Antikörper (C-Term) (ABIN6991916)

Target: FIL1h (Interleukin 1 eta (FIL1h))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FIL1h Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-FIL1h Antikörper

Bindungsspezifität: C-Term

Spezifität: IL-36B antibody is human specific. At least two isoforms of IL-36B are known to exist, this antibody will only detect the longer isoform. IL-36B antibody will not cross-react with IL-36A or IL-36G.

Aufreinigung: IL-36B antibody is affinity chromatography purified via peptide column.

Immunogen: IL-36B antibody was raised against a 16 amino acid peptide near the carboxy terminus of human IL-36B. The immunogen is located within the last 50 amino acids of IL-36B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IL-36B antibody can be used for detection of IL-36B by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: IL-36B antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: IL-36B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu FIL1h

Target: FIL1h (Interleukin 1 eta (FIL1h))

Andere Bezeichnung: IL-36B

Hintergrund: IL-36B is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36B is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP (2). Like the related proteins IL-36A and IL-36G, IL-36B requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (3). The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells (4).

Molekulargewicht: Predicted: 18 kDa

Observed: 17 kDa

Gen-ID: 27177

NCBI Accession: NP_055253

UniProt: Q9NZH7