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FIL1h Antikörper

FIL1h Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal Jacky-1 unconjugated
Produktnummer ABIN5564285
  • Target Alle FIL1h Produkte
    FIL1h (Interleukin 1 eta (FIL1h))
    Reaktivität
    • 30
    • 1
    Human
    Wirt
    • 25
    • 5
    Maus
    Klonalität
    • 27
    • 3
    Monoklonal
    Konjugat
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FIL1h Antikörper ist unkonjugiert
    Applikation
    • 23
    • 18
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    Recognizes human IL-36beta.
    Kreuzreaktivität
    Human
    Keine Kreuzreaktivität
    Maus
    Kreuzreaktivität (Details)
    Does not cross-react with mouse IL-36beta and IL-36gamma.
    Reinheit
    >95 % (SDS-PAGE)
    Immunogen
    Recombinant human IL-36beta.
    Klon
    Jacky-1
    Isotyp
    IgG1
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Haltbarkeit
    12 months
  • Target
    FIL1h (Interleukin 1 eta (FIL1h))
    Andere Bezeichnung
    IL-36beta (FIL1h Produkte)
    Synonyme
    2310043N20Rik antikoerper, Il36b antikoerper, FIL1 antikoerper, FIL1-(ETA) antikoerper, FIL1H antikoerper, FILI-(ETA) antikoerper, IL-1F8 antikoerper, IL-1H2 antikoerper, IL1-ETA antikoerper, IL1F8 antikoerper, IL1H2 antikoerper, Il1f8 antikoerper, interleukin 1 family, member 8 antikoerper, interleukin 36 beta antikoerper, interleukin 36, beta antikoerper, Il1f8 antikoerper, IL36B antikoerper, Il36b antikoerper
    Hintergrund
    IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
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